The Cannon fires a piercing blue laser at a satellite in space orbiting Norion, which then reflects off four panels into a final dish, from which a swirling orange laser is projected. The laser moves to incapacitate a target before it can impact. The Cannon is powered by three Fedtech Plasma Generators, A, B and C, all of which are knocked offline when the Space Pirates attack Norion. Without them, the Cannon is unable to be fired to destroy the Leviathan Seed coming Norion's way. Samus Aran, Gandrayda, Ghor and Rundas are ordered to Norion to reactivate the Generators, but Ghor ends up holding off enemies for Samus and Gandrayda states that "machines aren't my thing", leaving Samus to reactivate Generator A while Rundas activates B. After Samus battles Meta Ridley, she reactivates C and rushes back to the Cargo Hub, barely joining the other hunters on the elevator up to the Control Tower.
Samus begins attempting to fire the Cannon, but Dark Samus ambushes the Bounty Hunters and leaves them crippled. Samus manages to excessively force herself to press the final activation button, which destroys the Seed, before she loses consciousness for a month.