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Omega (Ω) is the Greek letter for "great" or "end". Omega may refer to several subjects in the Metroid series. Each one shares a close similarity to the name's concept:
Omega Metroid, the final and most powerful stage in the Metroid life cycle, except for the Queen
Final Omega's chamber, a room in Area 7
Omega Research, a room in the Phazon Mines
Omega Pirate, the most powerful Elite Pirate in Metroid Prime
Omega Pirate Absorption System, Space Pirate technology
Emperor Ing, "the alpha and omega" of the Ing according to the Logbook
Omega Cannon, the final and most powerful beam weapon in Metroid Prime Hunters
Omega Ridley, the final Leviathan guardian and Phazon-enhanced form of Ridley
Omega Hopper, a large Hopper
Omega Pirate, the Omega Pirate's battle theme
Omega Ridley, Omega Ridley's battle theme
Boss Omega, the Omega Metroid's battle theme in Samus Returns