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The Metroid Prime Theme is, as the name implies, the main theme of Metroid Prime. It is also featured in the Opening/Menu (Metroid Prime) song in Super Smash Bros. Brawl, though a narration by Jay Ward was added in the part where the opening theme is heard. The overall beat was similar to that of the main theme music for Metroid, although it included crackling and squeaking noises.
The theme is present in Metroid Prime 2: Echoes Bonus Disc, where it is used in The Metroid Chronicle while playing a movie with clips of Prime. Metroid Prime Trilogy also features the theme as one song that can be purchased in the Soundtrack Gallery.
A few notes of this theme can be heard at the start of the Metroid: Other M Action Story trailer. The music turns into an orchestral version of Vs. Ridley. Part of the theme plays on the Other M Title Screen. The same part of the theme also plays at several other points in the game: during the introduction when Samus detects the Bottle Ship's distress signal, and later when she first encounters the 07th Platoon.